10
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60675 | AMPK activator 2 | AMPK | |
AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer ... | |||
T60675L | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK |
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and mi... | |||
T23734 | AMPK activator C2 | Compound 2,Compound-2,C2 | |
AMPK activator C2 is an AMPK allosteric activator. | |||
T7362 | O-304 | AMPK | |
O-304 is a pan-activator of AMP-activated protein kinase (AMPK). | |||
T8526 | Metformin | 1,1-Dimethylbiguanide | Mitophagy , AMPK , Autophagy |
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm... | |||
T8532 | IM156 | OXPHOS | |
IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in anima... | |||
T63177 | AMPK activator 8 | ||
AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to... | |||
T63117 | AMPK activator 7 | ||
AMPK activator 7 (compound I-3-24) is an AMPK activator (EC50: 8.8 nM). AMPK activator 7 can be used in studies involving AMPK disorders, particularly type 2 diabetes, hyperglycaemia, metabolic syndrome, obesity, hyperch... | |||
T72690 | AMPK activator 9 | ||
AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 µM, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its ... | |||
T78095 | Demethyleneberberine chloride | NF-κB | |
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-κB pathway and modulating the equilibrium of Th cells. It is ... |